Description
Overview: Hepatitis E is a viral liver disease transmitted primarily through contaminated drinking water (fecal-oral route). The body produces IgM antibodies as the first line of defense against the virus. A positive Anti-HEV IgM result confirms that the infection is acute (happening right now or very recently).
Clinical Significance:
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Acute Diagnosis: Differentiates Hepatitis E from other types of viral hepatitis (like A, B, or C) which have similar symptoms.
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High-Risk Groups: While most people recover on their own, Hepatitis E can be dangerous for:
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Pregnant Women: Can lead to severe liver failure and fetal loss, especially in the third trimester.
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Immunocompromised Patients: Those with weak immune systems or chronic liver disease.
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When is this test recommended?
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To investigate symptoms of acute hepatitis, such as jaundice (yellowing of skin/eyes), dark urine, pale stools, fatigue, nausea, and abdominal pain.
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During outbreaks of waterborne illness.
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For pregnant women presenting with liver dysfunction.
Sample Requirements:
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Specimen: Serum.
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Container: Gold Top (SST) or Red Top Tube.
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Preparation: No fasting is required.
